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Effect of genotyping error in model-free linkage analysis using microsatellite or single-nucleotide polymorphism marker maps

Errors while genotyping are inevitable and can reduce the power to detect linkage. However, does genotyping error have the same impact on linkage results for single-nucleotide polymorphism (SNP) and microsatellite (MS) marker maps? To evaluate this question we detected genotyping errors that are con...

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Detalles Bibliográficos
Autores principales: Thompson, Cheryl L, Baechle, Dan, Lu, Qing, Mathew, George, Song, Yeunjoo, Iyengar, Sudha K, Gray-McGuire, Courtney, Goddard, Katrina AB
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866781/
https://www.ncbi.nlm.nih.gov/pubmed/16451614
http://dx.doi.org/10.1186/1471-2156-6-S1-S153