Precision and type I error rate in the presence of genotype errors and missing parental data: a comparison between the original transmission disequilibrium test (TDT) and TDTae statistics

BACKGROUND: Two factors impacting robustness of the original transmission disequilibrium test (TDT) are: i) missing parental genotypes and ii) undetected genotype errors. While it is known that independently these factors can inflate false-positive rates for the original TDT, no study has considered...

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Detalles Bibliográficos
Autores principales: Barral, Sandra, Haynes, Chad, Levenstien, Mark A, Gordon, Derek
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866784/
https://www.ncbi.nlm.nih.gov/pubmed/16451611
http://dx.doi.org/10.1186/1471-2156-6-S1-S150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866784/
https://www.ncbi.nlm.nih.gov/pubmed/16451611
http://dx.doi.org/10.1186/1471-2156-6-S1-S150

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