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Identifying susceptibility genes by using joint tests of association and linkage and accounting for epistasis

Simulated Genetic Analysis Workshop14 data were analyzed by jointly testing linkage and association and by accounting for epistasis using a candidate gene approach. Our group was unblinded to the "answers." The 48 single-nucleotide polymorphisms (SNPs) within the six disease loci were anal...

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Detalles Bibliográficos
Autores principales: Millstein, Joshua, Siegmund, Kimberly D, Conti, David V, Gauderman, W James
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866788/
https://www.ncbi.nlm.nih.gov/pubmed/16451607
http://dx.doi.org/10.1186/1471-2156-6-S1-S147