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Methods for detecting gene × gene interaction in multiplex extended pedigrees

Complex diseases are multifactorial in nature and can involve multiple loci with gene × gene and gene × environment interactions. Research on methods to uncover the interactions between those genes that confer susceptibility to disease has been extensive, but many of these methods have only been dev...

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Detalles Bibliográficos
Autores principales: Brock, Guy N, Maher, Brion S, Goldstein, Toby H, Cooper, Margaret E, Marazita, Mary L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866791/
https://www.ncbi.nlm.nih.gov/pubmed/16451604
http://dx.doi.org/10.1186/1471-2156-6-S1-S144