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Standard linkage and association methods identify the mechanism of four susceptibility genes for a simulated complex disease

The simulated dataset of the Genetic Analysis Workshop 14 provided affection status and the presence or absence of 12 traits. It was determined that all affected individuals must have traits E, F and H (EFH phenotype) and they must also have either trait B (B subtype) or traits C, D, and G (CDG subt...

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Detalles Bibliográficos
Autores principales: Pankratz, Nathan, Edenberg, Ellen, Foroud, Tatiana
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866793/
https://www.ncbi.nlm.nih.gov/pubmed/16451602
http://dx.doi.org/10.1186/1471-2156-6-S1-S142