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Construction of endophenotypes for complex diseases in the presence of heterogeneity

Endophenotypes such as behavior disorders have been increasingly adopted in genetic studies for complex traits. For efficient gene mapping, it is essential that an endophenotype is associated with the disease of interest and is inheritable or co-segregating within families. In this study, we propose...

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Detalles Bibliográficos
Autores principales: Chen, Chien-Hsiun, Kuo, Chih-Ling, Lin, Michael CP, Liang, Yu-Jen, Fann, Cathy SJ
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866797/
https://www.ncbi.nlm.nih.gov/pubmed/16451598
http://dx.doi.org/10.1186/1471-2156-6-S1-S139