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Construction of endophenotypes for complex diseases in the presence of heterogeneity
Endophenotypes such as behavior disorders have been increasingly adopted in genetic studies for complex traits. For efficient gene mapping, it is essential that an endophenotype is associated with the disease of interest and is inheritable or co-segregating within families. In this study, we propose...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866797/ https://www.ncbi.nlm.nih.gov/pubmed/16451598 http://dx.doi.org/10.1186/1471-2156-6-S1-S139 |