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Effects of population structure on genetic association studies

Population-based case-control association is a promising approach for unravelling the genetic basis of complex diseases. One potential problem of this approach is the presence of population structure in the samples. Using the Collaborative Study on the Genetics of Alcoholism (COGA) single-nucleotide...

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Detalles Bibliográficos
Autores principales: Xu, Hongyan, Shete, Sanjay
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866830/
https://www.ncbi.nlm.nih.gov/pubmed/16451565
http://dx.doi.org/10.1186/1471-2156-6-S1-S109