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Selecting cases from nuclear families for case-control association analysis

We examine the efficiency of a number of schemes to select cases from nuclear families for case-control association analysis using the Genetic Analysis Workshop 14 simulated dataset. We show that with this simulated dataset comparing all affected siblings with unrelated controls is considerably more...

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Detalles Bibliográficos
Autores principales: Moore, Rachael M, Pinel, Tracy, Zhao, Jing Hua, March, Ruth, Jawaid, Ansar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866834/
https://www.ncbi.nlm.nih.gov/pubmed/16451561
http://dx.doi.org/10.1186/1471-2156-6-S1-S105