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Comparisons of case-selection approaches based on allele sharing and/or disease severity index: application to the GAW14 simulated data

For mapping complex disease traits, linkage studies are often followed by a case-control association strategy in order to identify disease-associated genes/single-nucleotide polymorphisms (SNPs). Substantial efforts are required in selecting the most informative cases from a large collection of affe...

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Detalles Bibliográficos
Autores principales: Liu, Chunyu, Cupples, L Adrienne, Dupuis, Josée
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866836/
https://www.ncbi.nlm.nih.gov/pubmed/16451559
http://dx.doi.org/10.1186/1471-2156-6-S1-S103