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Molecular Mechanisms of the Diabetogenic Effects of Arsenic: Inhibition of Insulin Signaling by Arsenite and Methylarsonous Acid

BACKGROUND: Increased prevalences of diabetes mellitus have been reported among individuals chronically exposed to inorganic arsenic (iAs). However, the mechanisms underlying the diabetogenic effects of iAs have not been characterized. We have previously shown that trivalent metabolites of iAs, arse...

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Detalles Bibliográficos
Autores principales: Paul, David S., Harmon, Anne W., Devesa, Vicenta, Thomas, David J., Stýblo, Miroslav
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1867998/
https://www.ncbi.nlm.nih.gov/pubmed/17520061
http://dx.doi.org/10.1289/ehp.9867