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Evolutionary origins of insulin resistance: a behavioral switch hypothesis

BACKGROUND: Insulin resistance, which can lead to a number of diseases including type 2 diabetes and coronary heart disease, is believed to have evolved as an adaptation to periodic starvation. The "thrifty gene" and "thrifty phenotype" hypotheses constitute the dominant paradigm...

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Detalles Bibliográficos
Autores principales: Watve, Milind G, Yajnik, Chittaranjan S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868084/
https://www.ncbi.nlm.nih.gov/pubmed/17437648
http://dx.doi.org/10.1186/1471-2148-7-61