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Conformational Proofreading: The Impact of Conformational Changes on the Specificity of Molecular Recognition

To perform recognition, molecules must locate and specifically bind their targets within a noisy biochemical environment with many look-alikes. Molecular recognition processes, especially the induced-fit mechanism, are known to involve conformational changes. This raises a basic question: Does molec...

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Detalles Bibliográficos
Autores principales: Savir, Yonatan, Tlusty, Tsvi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868595/
https://www.ncbi.nlm.nih.gov/pubmed/17520027
http://dx.doi.org/10.1371/journal.pone.0000468