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Conformational Proofreading: The Impact of Conformational Changes on the Specificity of Molecular Recognition
To perform recognition, molecules must locate and specifically bind their targets within a noisy biochemical environment with many look-alikes. Molecular recognition processes, especially the induced-fit mechanism, are known to involve conformational changes. This raises a basic question: Does molec...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868595/ https://www.ncbi.nlm.nih.gov/pubmed/17520027 http://dx.doi.org/10.1371/journal.pone.0000468 |