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Novel insights into RNAi off-target effects using C. elegans paralogs
BACKGROUND: In the few years since its discovery, RNAi has turned into a very powerful tool for the study of gene function by allowing post-transcriptional gene silencing. The RNAi mechanism, which is based on the introduction of a double-stranded RNA (dsRNA) trigger whose sequence is similar to tha...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868761/ https://www.ncbi.nlm.nih.gov/pubmed/17445269 http://dx.doi.org/10.1186/1471-2164-8-106 |