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A forward-backward fragment assembling algorithm for the identification of genomic amplification and deletion breakpoints using high-density single nucleotide polymorphism (SNP) array

BACKGROUND: DNA copy number aberration (CNA) is one of the key characteristics of cancer cells. Recent studies demonstrated the feasibility of utilizing high density single nucleotide polymorphism (SNP) genotyping arrays to detect CNA. Compared with the two-color array-based comparative genomic hybr...

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Detalles Bibliográficos
Autores principales: Yu, Tianwei, Ye, Hui, Sun, Wei, Li, Ker-Chau, Chen, Zugen, Jacobs, Sharoni, Bailey, Dione K, Wong, David T, Zhou, Xiaofeng
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868765/
https://www.ncbi.nlm.nih.gov/pubmed/17477871
http://dx.doi.org/10.1186/1471-2105-8-145