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Distinct phospholipase A2 enzymes regulate prostaglandin E2 and F2alpha production by bovine endometrial epithelial cells

BACKGROUND: The rate-limiting step in prostaglandin (PG) biosynthesis is catalyzed by phospholipase A2 (PLA2) enzymes which hydrolyze arachidonic acid from membrane phospholipids. Despite their importance in uterine PG production, little is known concerning the specific PLA2 enzymes that regulate ar...

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Detalles Bibliográficos
Autores principales: Tithof, Patricia K, Roberts, Mary P, Guan, Wei, Elgayyar, Mona, Godkin, James D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868772/
https://www.ncbi.nlm.nih.gov/pubmed/17459165
http://dx.doi.org/10.1186/1477-7827-5-16