Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk

INTRODUCTION: Certain rare, familial mutations in the ATM, BRCA1, BRCA2, CHEK2 or TP53 genes increase susceptibility to breast cancer but it has not, until now, been clear whether common polymorphic variants in the same genes also increase risk. METHODS: We have attempted a comprehensive, single nuc...

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Detalles Bibliográficos
Autores principales: Baynes, Caroline, Healey, Catherine S, Pooley, Karen A, Scollen, Serena, Luben, Robert N, Thompson, Deborah J, Pharoah, Paul DP, Easton, Douglas F, Ponder, Bruce AJ, Dunning, Alison M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868915/
https://www.ncbi.nlm.nih.gov/pubmed/17428325
http://dx.doi.org/10.1186/bcr1669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868915/
https://www.ncbi.nlm.nih.gov/pubmed/17428325
http://dx.doi.org/10.1186/bcr1669

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