Normalization of two-channel microarrays accounting for experimental design and intensity-dependent relationships

In normalizing two-channel expression arrays, the ANOVA approach explicitly incorporates the experimental design in its model, and the MA plot-based approach accounts for intensity-dependent biases. However, both approaches can lead to inaccurate normalization in fairly common scenarios. We propose...

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Detalles Bibliográficos
Autores principales: Dabney, Alan R, Storey, John D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868928/
https://www.ncbi.nlm.nih.gov/pubmed/17391524
http://dx.doi.org/10.1186/gb-2007-8-3-r44

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868928/
https://www.ncbi.nlm.nih.gov/pubmed/17391524
http://dx.doi.org/10.1186/gb-2007-8-3-r44

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