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Mutation screen and association studies in the Diacylglycerol O-acyltransferase homolog 2 gene (DGAT2), a positional candidate gene for early onset obesity on chromosome 11q13

BACKGROUND: DGAT2 is a promising candidate gene for obesity because of its function as a key enzyme in fat metabolism and because of its localization on chromosome 11q13, a linkage region for extreme early onset obesity detected in our sample. We performed a mutation screen in 93 extremely obese chi...

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Detalles Bibliográficos
Autores principales: Friedel, Susann, Reichwald, Kathrin, Scherag, André, Brumm, Harald, Wermter, Anne-Kathrin, Fries, Hans-Rudolf, Koberwitz, Kerstin, Wabitsch, Martin, Meitinger, Thomas, Platzer, Matthias, Biebermann, Heike, Hinney, Anke, Hebebrand, Johannes
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1871603/
https://www.ncbi.nlm.nih.gov/pubmed/17477860
http://dx.doi.org/10.1186/1471-2156-8-17