Traditional Nonsteroidal Anti-Inflammatory Drugs and Postmenopausal Hormone Therapy: A Drug–Drug Interaction?

BACKGROUND: Suppression of prostacyclin (PGI(2)) is implicated in the cardiovascular hazard from inhibitors of cyclooxygenase (COX)-2. Furthermore, estrogen confers atheroprotection via COX-2–dependent PGI(2) in mice, raising the possibility that COX inhibitors may undermine the cardioprotection, su...

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Detalles Bibliográficos
Autores principales: García Rodríguez, Luis Alberto, Egan, Karine, FitzGerald, Garret A
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1872041/
https://www.ncbi.nlm.nih.gov/pubmed/17518513
http://dx.doi.org/10.1371/journal.pmed.0040157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1872041/
https://www.ncbi.nlm.nih.gov/pubmed/17518513
http://dx.doi.org/10.1371/journal.pmed.0040157

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