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Beyond the 3′ end: experimental validation of extended transcript isoforms

High throughput EST and full-length cDNA sequencing have revealed extensive variations at the 3′ ends of mammalian transcripts. Whether all of these changes are biologically meaningful has been the subject of controversy, as such, results may reflect in part transcription or polyadenylation leakage....

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Detalles Bibliográficos
Autores principales: Moucadel, Virginie, Lopez, Fabrice, Ara, Takeshi, Benech, Philippe, Gautheret, Daniel
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874610/
https://www.ncbi.nlm.nih.gov/pubmed/17339231
http://dx.doi.org/10.1093/nar/gkm062