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Dynamic binding of Ku80, Ku70 and NF90 to the IL-2 promoter in vivo in activated T-cells

IL-2 gene expression in activated T-cells is initiated by chromatin remodeling at the IL-2 proximal promoter and conversion of a transcriptional repressor into a potent transcriptional activator. A purine-box regulator complex was purified from activated Jurkat T-cell nuclei based on sequence-specif...

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Detalles Bibliográficos
Autores principales: Shi, Lingfang, Qiu, Daoming, Zhao, Guohua, Corthesy, Blaise, Lees-Miller, Susan, Reeves, Westley H., Kao, Peter N.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874627/
https://www.ncbi.nlm.nih.gov/pubmed/17389650
http://dx.doi.org/10.1093/nar/gkm117