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Topology of Type II REases revisited; structural classes and the common conserved core

Type II restriction endonucleases (REases) are deoxyribonucleases that cleave DNA sequences with remarkable specificity. Type II REases are highly divergent in sequence as well as in topology, i.e. the connectivity of secondary structure elements. A widely held assumption is that a structural core o...

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Detalles Bibliográficos
Autores principales: Niv, Masha Y., Ripoll, Daniel R., Vila, Jorge A., Liwo, Adam, Vanamee, Éva S., Aggarwal, Aneel K., Weinstein, Harel, Scheraga, Harold A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874628/
https://www.ncbi.nlm.nih.gov/pubmed/17369272
http://dx.doi.org/10.1093/nar/gkm045