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Reversible gene knockdown in mice using a tight, inducible shRNA expression system
RNA interference through expression of short hairpin (sh)RNAs provides an efficient approach for gene function analysis in mouse genetics. Techniques allowing to control time and degree of gene silencing in vivo, however, are still lacking. Here we provide a generally applicable system for the tempo...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874634/ https://www.ncbi.nlm.nih.gov/pubmed/17376804 http://dx.doi.org/10.1093/nar/gkm122 |