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A non-covalent peptide-based carrier for in vivo delivery of DNA mimics

The dramatic acceleration in identification of new nucleic-acid-based therapeutic molecules has provided new perspectives in pharmaceutical research. However, their development is limited by their poor cellular uptake and inefficient trafficking. Here we describe a short amphipathic peptide, Pep-3,...

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Detalles Bibliográficos
Autores principales: Morris, May C., Gros, Edwige, Aldrian-Herrada, Gudrun, Choob, Michael, Archdeacon, John, Heitz, Frederic, Divita, Gilles
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874649/
https://www.ncbi.nlm.nih.gov/pubmed/17341467
http://dx.doi.org/10.1093/nar/gkm053