Structural insight into repair of alkylated DNA by a new superfamily of DNA glycosylases comprising HEAT-like repeats

3-methyladenine DNA glycosylases initiate repair of cytotoxic and promutagenic alkylated bases in DNA. We demonstrate by comparative modelling that Bacillus cereus AlkD belongs to a new, fifth, structural superfamily of DNA glycosylases with an alpha–alpha superhelix fold comprising six HEAT-like re...

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Detalles Bibliográficos
Autores principales: Dalhus, Bjørn, Helle, Ina Høydal, Backe, Paul H., Alseth, Ingrun, Rognes, Torbjørn, Bjørås, Magnar, Laerdahl, Jon K.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874660/
https://www.ncbi.nlm.nih.gov/pubmed/17395642
http://dx.doi.org/10.1093/nar/gkm039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874660/
https://www.ncbi.nlm.nih.gov/pubmed/17395642
http://dx.doi.org/10.1093/nar/gkm039

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