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Structural insight into repair of alkylated DNA by a new superfamily of DNA glycosylases comprising HEAT-like repeats
3-methyladenine DNA glycosylases initiate repair of cytotoxic and promutagenic alkylated bases in DNA. We demonstrate by comparative modelling that Bacillus cereus AlkD belongs to a new, fifth, structural superfamily of DNA glycosylases with an alpha–alpha superhelix fold comprising six HEAT-like re...
Autores principales: | Dalhus, Bjørn, Helle, Ina Høydal, Backe, Paul H., Alseth, Ingrun, Rognes, Torbjørn, Bjørås, Magnar, Laerdahl, Jon K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874660/ https://www.ncbi.nlm.nih.gov/pubmed/17395642 http://dx.doi.org/10.1093/nar/gkm039 |
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