Distance constraints between microRNA target sites dictate efficacy and cooperativity

MicroRNAs (miRNAs) have the potential to regulate the expression of thousands of genes, but the mechanisms that determine whether a gene is targeted or not are poorly understood. We studied the genomic distribution of distances between pairs of identical miRNA seeds and found a propensity for modera...

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Detalles Bibliográficos
Autores principales: Sætrom, Pål, Heale, Bret S.E., Snøve, Ola, Aagaard, Lars, Alluin, Jessica, Rossi, John J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874663/
https://www.ncbi.nlm.nih.gov/pubmed/17389647
http://dx.doi.org/10.1093/nar/gkm133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874663/
https://www.ncbi.nlm.nih.gov/pubmed/17389647
http://dx.doi.org/10.1093/nar/gkm133

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