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Distance constraints between microRNA target sites dictate efficacy and cooperativity
MicroRNAs (miRNAs) have the potential to regulate the expression of thousands of genes, but the mechanisms that determine whether a gene is targeted or not are poorly understood. We studied the genomic distribution of distances between pairs of identical miRNA seeds and found a propensity for modera...
Autores principales: | Sætrom, Pål, Heale, Bret S.E., Snøve, Ola, Aagaard, Lars, Alluin, Jessica, Rossi, John J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874663/ https://www.ncbi.nlm.nih.gov/pubmed/17389647 http://dx.doi.org/10.1093/nar/gkm133 |
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