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Molecular mechanism of upregulation of survivin transcription by the AT-rich DNA-binding ligand, Hoechst33342: evidence for survivin involvement in drug resistance

We have previously shown that hedamycin, a GC-rich DNA-binding antitumor agent, downregulates survivin transcription (Wu et al. (2005) Molecular mechanism of inhibition of survivin transcription by the GC-rich sequence selective DNA-binding antitumor agent, hedamycin: evidence of survivin downregula...

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Detalles Bibliográficos
Autores principales: Wu, Jianguo, Apontes, Pasha, Song, Lei, Liang, Ping, Yang, Lily, Li, Fengzhi
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874665/
https://www.ncbi.nlm.nih.gov/pubmed/17392340
http://dx.doi.org/10.1093/nar/gkm149