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Inhibitory Effect of Inflexinol on Nitric Oxide Generation and iNOS Expression via Inhibition of NF-κB Activation

Inflexinol, an ent-kaurane diterpenoid, was isolated from the leaves of Isodon excisus. Many diterpenoids isolated from the genus Isodon (Labiatae) have antitumor and antiinflammatory activities. We investigated the antiinflammatory effect of inflexinol in RAW 264.7 cells and astrocytes. As a result...

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Detalles Bibliográficos
Autores principales: Lee, Jae Woong, Lee, Moon Soon, Kim, Tae Hun, Lee, Hwa Jeong, Hong, Seong Su, Noh, Young Hee, Hwang, Bang Yeon, Ro, Jai Seup, Hong, Jin Tae
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874678/
https://www.ncbi.nlm.nih.gov/pubmed/17541474
http://dx.doi.org/10.1155/2007/93148