Induction of MMP-9 release from human dermal fibroblasts by thrombin: involvement of JAK/STAT3 signaling pathway in MMP-9 release

BACKGROUND: It has been recognized that dermal fibroblasts and matrix metalloproteases (MMP) play crucial roles in wound healing process in skin. Thrombin was found to stimulate IL-8 release from human dermal fibroblasts (HDFs). However, little is known of the effect of thrombin on secretion of MMPs...

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Detalles Bibliográficos
Autores principales: Wang, Li, Luo, Jianmin, He, Shaoheng
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876221/
https://www.ncbi.nlm.nih.gov/pubmed/17480240
http://dx.doi.org/10.1186/1471-2121-8-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876221/
https://www.ncbi.nlm.nih.gov/pubmed/17480240
http://dx.doi.org/10.1186/1471-2121-8-14

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