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How accurate and statistically robust are catalytic site predictions based on closeness centrality?
BACKGROUND: We examine the accuracy of enzyme catalytic residue predictions from a network representation of protein structure. In this model, amino acid α-carbons specify vertices within a graph and edges connect vertices that are proximal in structure. Closeness centrality, which has shown promise...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876251/ https://www.ncbi.nlm.nih.gov/pubmed/17498304 http://dx.doi.org/10.1186/1471-2105-8-153 |