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A full Bayesian hierarchical mixture model for the variance of gene differential expression

BACKGROUND: In many laboratory-based high throughput microarray experiments, there are very few replicates of gene expression levels. Thus, estimates of gene variances are inaccurate. Visual inspection of graphical summaries of these data usually reveals that heteroscedasticity is present, and the s...

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Detalles Bibliográficos
Autores principales: Manda, Samuel OM, Walls, Rebecca E, Gilthorpe, Mark S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876253/
https://www.ncbi.nlm.nih.gov/pubmed/17439644
http://dx.doi.org/10.1186/1471-2105-8-124