Polymorphisms, Mutations, and Amplification of the EGFR Gene in Non-Small Cell Lung Cancers

BACKGROUND: The epidermal growth factor receptor (EGFR) gene is the prototype member of the type I receptor tyrosine kinase (TK) family and plays a pivotal role in cell proliferation and differentiation. There are three well described polymorphisms that are associated with increased protein producti...

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Detalles Bibliográficos
Autores principales: Nomura, Masaharu, Shigematsu, Hisayuki, Li, Lin, Suzuki, Makoto, Takahashi, Takao, Estess, Pila, Siegelman, Mark, Feng, Ziding, Kato, Harubumi, Marchetti, Antonio, Shay, Jerry W, Spitz, Margaret R, Wistuba, Ignacio I, Minna, John D, Gazdar, Adi F
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876407/
https://www.ncbi.nlm.nih.gov/pubmed/17455987
http://dx.doi.org/10.1371/journal.pmed.0040125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876407/
https://www.ncbi.nlm.nih.gov/pubmed/17455987
http://dx.doi.org/10.1371/journal.pmed.0040125

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