Phagocytosis of Cholesteryl Ester Is Amplified in Diabetic Mouse Macrophages and Is Largely Mediated by CD36 and SR-A

Type 2 diabetes (T2D) is associated with accelerated atherosclerosis, which accounts for approximately 75% of all diabetes-related deaths. Here we investigate the link between diabetes and macrophage cholesteryl ester accumulation. When diabetic (db/db) mice are given cholesteryl ester intraperitone...

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Detalles Bibliográficos
Autores principales: Guest, Christopher B., Hartman, Matthew E., O'Connor, Jason C., Chakour, Kenneth S., Sovari, Ali A., Freund, Gregory G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876806/
https://www.ncbi.nlm.nih.gov/pubmed/17551591
http://dx.doi.org/10.1371/journal.pone.0000511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876806/
https://www.ncbi.nlm.nih.gov/pubmed/17551591
http://dx.doi.org/10.1371/journal.pone.0000511

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