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Phagocytosis of Cholesteryl Ester Is Amplified in Diabetic Mouse Macrophages and Is Largely Mediated by CD36 and SR-A
Type 2 diabetes (T2D) is associated with accelerated atherosclerosis, which accounts for approximately 75% of all diabetes-related deaths. Here we investigate the link between diabetes and macrophage cholesteryl ester accumulation. When diabetic (db/db) mice are given cholesteryl ester intraperitone...
Autores principales: | Guest, Christopher B., Hartman, Matthew E., O'Connor, Jason C., Chakour, Kenneth S., Sovari, Ali A., Freund, Gregory G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876806/ https://www.ncbi.nlm.nih.gov/pubmed/17551591 http://dx.doi.org/10.1371/journal.pone.0000511 |
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