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The lin-35/Rb and RNAi pathways cooperate to regulate a key cell cycle transition in C. elegans
BACKGROUND: The Retinoblastoma gene product (Rb) has been shown to regulate the transcription of key genes involved in cell growth and proliferation. Consistent with this, mutations in Rb are associated with numerous types of cancer making it a critical tumour suppressor gene. Its function is confer...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1877806/ https://www.ncbi.nlm.nih.gov/pubmed/17466069 http://dx.doi.org/10.1186/1471-213X-7-38 |