p53 Activation by Knockdown Technologies

Morpholino phosphorodiamidate antisense oligonucleotides (MOs) and short interfering RNAs (siRNAs) are commonly used platforms to study gene function by sequence-specific knockdown. Both technologies, however, can elicit undesirable off-target effects. We have used several model genes to study these...

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Detalles Bibliográficos
Autores principales: Robu, Mara E, Larson, Jon D, Nasevicius, Aidas, Beiraghi, Soraya, Brenner, Charles, Farber, Steven A, Ekker, Stephen C
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1877875/
https://www.ncbi.nlm.nih.gov/pubmed/17530925
http://dx.doi.org/10.1371/journal.pgen.0030078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1877875/
https://www.ncbi.nlm.nih.gov/pubmed/17530925
http://dx.doi.org/10.1371/journal.pgen.0030078

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