Supervised multivariate analysis of sequence groups to identify specificity determining residues

BACKGROUND: Proteins that evolve from a common ancestor can change functionality over time, and it is important to be able identify residues that cause this change. In this paper we show how a supervised multivariate statistical method, Between Group Analysis (BGA), can be used to identify these res...

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Detalles Bibliográficos
Autores principales: Wallace, Iain M, Higgins, Desmond G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1878507/
https://www.ncbi.nlm.nih.gov/pubmed/17451607
http://dx.doi.org/10.1186/1471-2105-8-135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1878507/
https://www.ncbi.nlm.nih.gov/pubmed/17451607
http://dx.doi.org/10.1186/1471-2105-8-135

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