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Supervised multivariate analysis of sequence groups to identify specificity determining residues
BACKGROUND: Proteins that evolve from a common ancestor can change functionality over time, and it is important to be able identify residues that cause this change. In this paper we show how a supervised multivariate statistical method, Between Group Analysis (BGA), can be used to identify these res...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1878507/ https://www.ncbi.nlm.nih.gov/pubmed/17451607 http://dx.doi.org/10.1186/1471-2105-8-135 |