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Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE

BACKGROUND: The CC chemokine receptors CCR1, CCR2 and CCR5 are critical for the recruitment of mononuclear phagocytes to the central nervous system (CNS) in multiple sclerosis (MS) and other neuroinflammatory diseases. Mononuclear phagocytes are effector cells capable of phagocytosing myelin and dam...

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Detalles Bibliográficos
Autores principales: Eltayeb, Sana, Berg, Anna-Lena, Lassmann, Hans, Wallström, Erik, Nilsson, Maria, Olsson, Tomas, Ericsson-Dahlstrand, Anders, Sunnemark, Dan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884136/
https://www.ncbi.nlm.nih.gov/pubmed/17484785
http://dx.doi.org/10.1186/1742-2094-4-14