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Arthritis suppression by NADPH activation operates through an interferon-β pathway

BACKGROUND: A polymorphism in the activating component of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex, neutrophil cytosolic factor 1 (NCF1), has previously been identified as a regulator of arthritis severity in mice and rats. This discovery resulted in a search for NADPH...

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Detalles Bibliográficos
Autores principales: Olofsson, Peter, Nerstedt, Annika, Hultqvist, Malin, Nilsson, Elisabeth C, Andersson, Sofia, Bergelin, Anna, Holmdahl, Rikard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884140/
https://www.ncbi.nlm.nih.gov/pubmed/17490473
http://dx.doi.org/10.1186/1741-7007-5-19