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Human immunodeficiency virus type 1 efficiently binds to human fetal astrocytes and induces neuroinflammatory responses independent of infection

BACKGROUND: HIV-1 infects human astrocytes in vitro and in vivo but the frequency of infected cells is low and its biological significance is unknown. In studies in vitro, recombinant gp120 alone can induce profound effects on astrocyte biology, suggesting that HIV-1 interaction with astrocytes and...

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Detalles Bibliográficos
Autores principales: Li, Jinliang, Bentsman, Galina, Potash, Mary Jane, Volsky, David J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884168/
https://www.ncbi.nlm.nih.gov/pubmed/17498309
http://dx.doi.org/10.1186/1471-2202-8-31