Stringent and reproducible tetracycline-regulated transgene expression by site-specific insertion at chromosomal loci with pre-characterised induction characteristics

BACKGROUND: The ability to regulate transgene expression has many applications, mostly concerning the analysis of gene function. Desirable induction characteristics, such as low un-induced expression, high induced expression and limited cellular heterogeneity, can be seriously impaired by chromosoma...

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Detalles Bibliográficos
Autores principales: Brough, Rachel, Papanastasiou, Antigoni M, Porter, Andrew CG
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884169/
https://www.ncbi.nlm.nih.gov/pubmed/17493262
http://dx.doi.org/10.1186/1471-2199-8-30

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884169/
https://www.ncbi.nlm.nih.gov/pubmed/17493262
http://dx.doi.org/10.1186/1471-2199-8-30

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