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Involvement of Src kinases and PLCγ2 in clot retraction

The integrin α(IIb)β(3) plays a critical role in mediating clot retraction by platelets which is important in vivo in consolidating thrombus formation. Actin–myosin interaction is essential for clot retraction. In the present study, we demonstrate that the structurally distinct Src kinase inhibitors...

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Detalles Bibliográficos
Autores principales: Suzuki-Inoue, Katsue, Hughes, Craig E., Inoue, Osamu, Kaneko, Makoto, Cuyun-Lira, Olga, Takafuta, Toshiro, Watson, Steve P., Ozaki, Yukio
Formato: Texto
Lenguaje:English
Publicado: Pergamon Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884692/
https://www.ncbi.nlm.nih.gov/pubmed/17055557
http://dx.doi.org/10.1016/j.thromres.2006.09.003