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Differentiating between Near- and Non-Cognate Codons in Saccharomyces cerevisiae
BACKGROUND: Decoding of mRNAs is performed by aminoacyl tRNAs (aa-tRNAs). This process is highly accurate, however, at low frequencies (10(−3) – 10(−4)) the wrong aa-tRNA can be selected, leading to incorporation of aberrant amino acids. Although our understanding of what constitutes the correct or...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885216/ https://www.ncbi.nlm.nih.gov/pubmed/17565370 http://dx.doi.org/10.1371/journal.pone.0000517 |