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Differentiating between Near- and Non-Cognate Codons in Saccharomyces cerevisiae

BACKGROUND: Decoding of mRNAs is performed by aminoacyl tRNAs (aa-tRNAs). This process is highly accurate, however, at low frequencies (10(−3) – 10(−4)) the wrong aa-tRNA can be selected, leading to incorporation of aberrant amino acids. Although our understanding of what constitutes the correct or...

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Detalles Bibliográficos
Autores principales:	Plant, Ewan P., Nguyen, Phuc, Russ, Jonathan R., Pittman, Yvette R., Nguyen, Thai, Quesinberry, Jack T., Kinzy, Terri Goss, Dinman, Jonathan D.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885216/ https://www.ncbi.nlm.nih.gov/pubmed/17565370 http://dx.doi.org/10.1371/journal.pone.0000517

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