A hierarchical approach employing metabolic and gene expression profiles to identify the pathways that confer cytotoxicity in HepG2 cells

BACKGROUND: Free fatty acids (FFA) and tumor necrosis factor alpha (TNF-α) have been implicated in the pathogenesis of many obesity-related metabolic disorders. When human hepatoblastoma cells (HepG2) were exposed to different types of FFA and TNF-α, saturated fatty acid was found to be cytotoxic an...

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Detalles Bibliográficos
Autores principales: Li, Zheng, Srivastava, Shireesh, Yang, Xuerui, Mittal, Sheenu, Norton, Paul, Resau, James, Haab, Brian, Chan, Christina
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885270/
https://www.ncbi.nlm.nih.gov/pubmed/17498300
http://dx.doi.org/10.1186/1752-0509-1-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885270/
https://www.ncbi.nlm.nih.gov/pubmed/17498300
http://dx.doi.org/10.1186/1752-0509-1-21

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