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Whole-Genome Cartography of Estrogen Receptor α Binding Sites

Using a chromatin immunoprecipitation-paired end diTag cloning and sequencing strategy, we mapped estrogen receptor α (ERα) binding sites in MCF-7 breast cancer cells. We identified 1,234 high confidence binding clusters of which 94% are projected to be bona fide ERα binding regions. Only 5% of the...

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Detalles Bibliográficos
Autores principales: Lin, Chin-Yo, Vega, Vinsensius B, Thomsen, Jane S, Zhang, Tao, Kong, Say Li, Xie, Min, Chiu, Kuo Ping, Lipovich, Leonard, Barnett, Daniel H, Stossi, Fabio, Yeo, Ailing, George, Joshy, Kuznetsov, Vladimir A, Lee, Yew Kok, Charn, Tze Howe, Palanisamy, Nallasivam, Miller, Lance D, Cheung, Edwin, Katzenellenbogen, Benita S, Ruan, Yijun, Bourque, Guillaume, Wei, Chia-Lin, Liu, Edison T
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885282/
https://www.ncbi.nlm.nih.gov/pubmed/17542648
http://dx.doi.org/10.1371/journal.pgen.0030087